Several studies reported antiviral effects of ivermectin on RNA viruses such as Zika, dengue, yellow fever, West Nile, Hendra, Newcastle, Venezuelan equine encephalitis, chikungunya, Semliki Forest, Sindbis, Avian influenza A, Porcine Reproductive and Respiratory Syndrome, Human immunodeficiency virus type 1, and severe acute respiratory syndrome coronavirus 2.
Furthermore, there are some studies showing antiviral effects of ivermectin against DNA viruses such as Equine herpes type 1, BK polyomavirus, pseudorabies, porcine circovirus 2, and bovine herpesvirus 1. Ivermectin plays a role in several biological mechanisms, therefore it could serve as a potential candidate in the treatment of a wide range of viruses including COVID as well as other types of positive-sense single-stranded RNA viruses.
A few plants grow in the hot soils surrounding the geysers and the "Artists' Paintpots" of Yellowstone National Park. One such plant, which is a type of tropical panic grass, is a symbiosis that includes a fungus that colonizes the plant, and a virus that infects that fungus.
All three members of this symbiosis are necessary for survival in soils simmering at more than degrees Fahrenheit. In the laboratory, Roossinck has created symbioses between the same virus-infected fungus and other plants.
This has enabled every plant her group has tested to survive at these elevated soil temperatures, including tomato, she says, noting that she has pushed the soil temperature to degrees without killing the plant. Investigators have also found that certain viruses can render some plants drought tolerant, and at least one example of virally-conferred cold tolerance has been discovered-- discoveries that could become useful for expanding the ranges of crops.
Plants are often infected with "persistent viruses" that are passed down from generation to generation, perhaps over thousands of years, with viruses that are transmitted to nearly percent of their plant progeny, but that have never been shown to be transmitted from one plant to another.
Other beneficial viruses are the ancient retroviruses that long ago made a permanent home in the genome, or that left genes therein, said Roossinck. I was always a little disturbed at the bad rap they get, so it was very exciting for me to find good ones. Materials provided by American Society for Microbiology. Note: Content may be edited for style and length. Science News. Journal Reference : Marilyn J. Move over bacteria! This has caused a skewed view of these microbial creatures and quite possibly has prevented us from seeing the good they can do for our health.
But she does point out several critical factors already known about viruses in the human body. We have a population of viruses in the gut, the skin, and even in the blood.
This particular fact has been known for well over forty years. The virome appears at a very young age and appears to be dynamic in the first months of life. But, eventually the population tends to settle. Each of us has a unique collection of viruses although there are some species common to us all. Many are bacteriophages, which target bacteria, but some can find a home in human cells. One of them happens to be in about half the population. The abundance of these particular viruses is still not clear but the fact remains, they are there, even when we are healthy.
A lack of infection does not alone constitute a friend, but Roossnick suggests there are beneficial viruses out there. Some may help us stay healthy and even more surprisingly, fend off infections. She also explains how one particular virus, known simply as GB-C, can help people who suffer from HIV by slowing down the progression of viral spread in the body. These are just two examples but Roossnick suggests this may only be the beginning.
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